Thursday, 31 July 2014

PREVENTION AND CONTROL OF CANCER


Prevention and control of cancer

Prevalence of cancer mortality due to this malignant disease has been on the increase since the beginning of 20 th century in western countries and recently also in eastern countries including India. This increase was mainly attributed to improved diagnostic facilities and methods,a better knowledge of the disease and better experience of doctors,an increased consciousness of the people prompting to seek more medical advice,increased suspicion index among physicians and finally to the aging population. We have no authentic statistics for incidence in our country but hospital records show that it is rising.

Cancer is synonymous with malignant disease,which is characterized by abnormal growth of cells of the body of other parts to start a new nodule there. At present cancer is mainly divided into 4 groups viz, cancer affecting epithelial cells,sarcoma affecting connective tissue cells,lymphoma affecting lymphatic tissues and malignant growth of lymphoid cells,Leukemia affecting blood cells(blood cancer),however,each sub- divisions is not entirely one disease,but is believed to be a group of various diseases,with some common factors like an abnormal cell growth being a factor invariably common to all types of cancer .The dividing line is not clear between normal and cancer cells,and invasive erosion of the surrounding tissue..many benign tumors show some characteristics of local malignancy and some others are benign in the early stages but turn malignancy a wide unknown region lies in between malignancy and benignity, malignant disease can affect any tissue and any part of the body,some tissues show a higher  affective than others,some tissues are more prone than others to get metastatic deposit,some primary growths show a particular predilection for some particular parts of the body.

Early detection and treatment
---------------------------------------



Early detection,diagnosis and treatment has been the mainstay of the concept of prevention of cancer because firstly the known methods of treatment can result in high cure rate,at least a high years of survival rate,.Secondly, all our other preventive measures at present depend upon epidemiological information collected from the patients. The early detection and follow up reveal the carcinogenic factors,precancerous conditions and their progress and provide material in the form of the patient and biopsy for further study the early diagnosis and treatment halts or limits the spread of cancer and disability.
Follow up of all cases treated is an essential part of the anticancer pro gramme because after the 5 years cure promised by early proper treatment, a number of them develop recurrence and secondaries in vital organs like brain and lungs.


Cytology and mass radiography have helped in the detection of early cancers. many cancers originating in epithelial tissues at a very early stage exfoliate cells showing characteristics of malignancy,in many case much before any detectable lesion appear cytological test was first developed,and has been applied most successfully and extensively,for early detection of cancer of the cervix and can now be used in the early detection of lungs cancer 1960 to 1970 in western countries like USA the mortality rate from lung cancer exceeds mortality from pulmonary tuberculosis,therefore,this routine technique is often used in tuberculosis wards and follow up persons found to have or suspected pulmonary disease on mass chest x-ray survey ,further application of cytological test to cancers of gastric,pro static,bladder and other organs and systems now being unexplored radiography is also being used for detection of cancer of upper gastrointestinal tract after a preliminary examination of older age males for occult blood in stools,anemia,those who show positive findings are given full radio graphic examinations and cytological examinations wherever applicable of radioisotopes in the detection of some of later,and some cancers is also being rapidly developed.


Specialized Hospitals equipped with administrative,technical and professional resources for diagnostic,therapeutic,epidemiological and research work  are needed at various places. for routine periodical checks of the apparently healthy persons are necessary to be established at central places. also help to stimulate the professional and public interesting these central places field teams can be sent out. All can be referred for further studies to the centers by these teams and private profession this purpose a high suspicion index has to be created in all .sufficient literature in order to acquaint them with early signs of malignancy and precancerous conditions in easily accessible parts of body viz skin,rectum,breast,female genital parts and information regarding common carcinogenic factors should be made available.

Mas screening envisages periodic examinations of population,usually restricted to persons of 30 years and over,to detect early cancer and precancerous states. The periodicity of such examinations will vary according to the resources available,but they should be repeated as often as practicable. Such mass surveys are ideal in cancer prevention pro-grammes but throw an enormous burden on available medical man power and resources. Therefore,scope of mass examination can be determined only in the light of health and economic condition in a country,but in the long run may prove to be cheaper than the treatment of established diseases.

Primary prevention-Even if all the existing cases were detected we have no facilities to treat even ten percent of them,detection by mass survey itself and then dealing with all the detected cases are formidable tasks. It is,therefore,necessary to use the available knowledge for primary prevention of cancer in its precancerous stage .primary prevention can be affected by:(a)Detection,recognition and prompt and appropriate treatment of precancerous conditions.(b)Elimination of protection against genetic factors known or believed to be involved in carcinogens-is.

Precancerous conditions:These has been identified in many instances. These conditions do not show clinical,histological,or cytological evidence for longtime,but subsequently become malignant. Signs and symptoms of precancerous lesions are recognizable by the alert patient himself in many sites including the skin,mouth,pharynx,stomach,colon,female reproductive organs and breasts. The public may be in possession of knowledge and that may cause them to seek medical advice. The persons above 30 years should get periodical check even if there is no sign and symptom of diseases,namely discharge of blood or serous fluid from any of the natural openings,unexplained mass in anywhere in the body,alteration in bowel habits and appetite,sudden difficulty in swallowing persistent and progressive cough,unexplained loss of weight or fatigue,rapid growth,ulceration and bleeding.



Carcinogen: identification,living and working environments,cancer education and research are important per-requisite for cancer prevention.